Vascular calcification, bone and mineral metabolism after kidney transplantation

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Early chronic kidney disease-mineral bone disorder stimulates vascular calcification

The chronic kidney disease-mineral and bone disorder (CKD-MBD) syndrome is an extremely important complication of kidney diseases. Here we tested whether CKD-MBD causes vascular calcification in early kidney failure by developing a mouse model of early CKD in a background of atherosclerosis-stimulated arterial calcification. CKD equivalent in glomerular filtration reduction to human CKD stage 2...

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Bone metabolism and vascular calcification.

Osteoporosis and atherosclerosis are chronic degenerative diseases which have been considered to be independent and whose common characteristic is increasing incidence with age. At present, growing evidence indicates the existence of a correlation between cardiovascular disease and osteoporosis, irrespective of age. The morbidity and mortality of osteoporosis is mainly related to the occurrence...

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ژورنال

عنوان ژورنال: World Journal of Transplantation

سال: 2015

ISSN: 2220-3230

DOI: 10.5500/wjt.v5.i4.222